A primary health care (PHC)–orientation of health systems is both a technical and a political process. It may require policy reform and the redistribution of resources and roles, which will inevitably encounter both support as well as resistance. The political economy around PHC–orientation considers “who” might support or oppose certain aspects of a reform, as well as “how” and “why” they might support or oppose them. A primary health care (PHC)–orientation of health systems is both a technical and a political process. It may require policy reform and the redistribution of resources and roles, which will inevitably encounter both support as well as resistance. The political economy around PHC–orientation considers “who” might support or oppose certain aspects of a reform, as well as “how” and “why” they might support or oppose them. Find out more about WHO’s work to explore the political economy of PHC-oriented reforms through a series of country cases developed as part of WHO’s PHC Implementation Solutions Initiative at https://www.who.int/teams/primary-health-care/evidence-and-innovation/primary-health-care-implementation-solutions-initiative